Marburg hemorrhagic fever in Durba and Watsa, Democratic Republic of the Congo: clinical documentation, features of illness, and treatment.

نویسندگان

  • Robert Colebunders
  • Antoine Tshomba
  • Maria D Van Kerkhove
  • Daniel G Bausch
  • Pat Campbell
  • Modeste Libande
  • Patricia Pirard
  • Florimond Tshioko
  • Simon Mardel
  • Sabue Mulangu
  • Hilde Sleurs
  • Pierre E Rollin
  • Jean-Jacques Muyembe-Tamfum
  • Benjamin Jeffs
  • Matthias Borchert
چکیده

The objective of the present study was to describe day of onset and duration of symptoms of Marburg hemorrhagic fever (MHF), to summarize the treatments applied, and to assess the quality of clinical documentation. Surveillance and clinical records of 77 patients with MHF cases were reviewed. Initial symptoms included fever, headache, general pain, nausea, vomiting, and anorexia (median day of onset, day 1-2), followed by hemorrhagic manifestations (day 5-8+), and terminal symptoms included confusion, agitation, coma, anuria, and shock. Treatment in isolation wards was acceptable, but the quality of clinical documentation was unsatisfactory. Improved clinical documentation is necessary for a basic evaluation of supportive treatment.

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عنوان ژورنال:
  • The Journal of infectious diseases

دوره 196 Suppl 2  شماره 

صفحات  -

تاریخ انتشار 2007